MeSeBlog

Random monomer orders -> random conformations -> random shapes, mechanical properties and surface structures -> random functions

Sunday, November 16, 2014

PDF Version of "Enzymes and Molecular Machines" Etc.

I just uploaded a PDF version of the fundamental paper here "Enzymes and Molecular Machines Can Be Selected from Random Copolymers" to Academia.edu.

Enjoy.

(15 pages.!?)
Posted by John Kennard at 3:06 PM No comments:
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MeSe for Dummies ;^)~

Just read from the earliest post of this blog forward.

History of a Theory

The theory of mechanomeric selection began as a private study of senescence and gerontotherapy back in the early '90s, everything examined therein leading to the question, "Wouldn't it be nice to have an enzyme or protein machine to--?"

From there it went within a year to a study and theory of protein development (using random messenger RNAs and cell-free ribosomal protein-synthesizing systems).

And from there it went to the more general study and theory of mechanomeric development, applying itself to itself over and over, the original project now being a barely-alluded-to set of medical applications of a tremendously more general technological study with tremendously general potentials.

The main study exists as a rough informal 22K-word monograph and notes, Random Mechanomers and Mechanomeric Engineering.

A 2K-word condensation was posted to Usenet two years ago, using the earlier terminology "Empirical Mechanomeric Development",

Message-ID:dc9ea25d-2a97-4433-b12b-9badce785655@c5g2000vbh.googlegroups.com

http://groups.google.com/group/sci.bio.technology/browse_thread/thread/6eb4ad05137621be

in order to make sure the technology was out there, prevent patenting/monopolization, and stake intellectual claim to it

The present pseudoblog "MeSeBlog" (originally "EMDblog) was set up a year ago as a sort of easygoing "Mechanomeric Selection FAQ", or even "Mechanomeric Selection for Dummies":

http://mechanomers.blogspot.com/

(start at the bottom, in classic blog fashion).

And finally the condensed report, with background, critical argument, fundamental technological description, and light examination of some medical and industrial applications, "Enzymes and Molecular Machines Can Be Selected from Random Copolymers", was posted to this blog at

http://mechanomers.blogspot.com/2012/03/enzymes-and-molecular-machines-can-be.html

and its critical argument and a link to the rest at Nanopaprika.eu - The International NanoScience Community at

http://www.nanopaprika.eu/profiles/blogs/enzymes-and-molecular-machines-can-be-selected-from-random

I need and am seeking a grant to finish the main monograph.

See also

  • John Kennard's Nanopaprika.eu/TINC Page

Nanopaprika.eu

  • The International Nano-Science Community

Proteopedia

  • 3D manipulation of mechanomers (mostly biopolymers, mostly proteins)

Lifeboat Foundation

Lifeboat Foundation(advisor)

(The Lifeboat Foundation is of course in no way responsible for nor does it necessarily share the opinions asserted in this or any of my other blogs.)


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      • PDF Version of "Enzymes and Molecular Machines" Etc.

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